Sunday, August 11, 2013

The pill that texts the doctor - from inside your body

pills Handle with care: The drugs we take to treat chronic illness can be as dangerous as the disease if wrongly used
As a species, the human race is messy.
We can be inconsistent, disorganised, mendacious, unpredictable and frequently bad at making the right decisions about what's really in our best interests.
Which means that being responsible for people in vulnerable situations - for example, chronic illness - can be fraught with difficulty. Because as cruel as disease can be, the consequences of human error can be just as bad.
According to the World Health Organisation around 50% of us fail to take medicines correctly, while over 50% of drugs are prescribed, dispensed or sold inappropriately.
Not only can this have horrifying consequences for patients, it also costs healthcare providers millions every year.
So technology to help avoid these situations could prove lucrative.
There's no shortage of drug reference apps, like Micromedex, but a number of start-ups are exploring more interactive routes.

Start Quote

There's tremendous confusion around appropriate use of medicines and how they work”
Andrew Thomson Proteus Digital Health
Talk it out
"Human beings aren't robots, and if they're asked to take medicines or do anything that requires very high levels of routine repetition they are going to find that really tough," says Andrew Thomson, chief executive of California-based Proteus Digital Health.
"The biggest burdens in our health system are about chronic disease, and people typically who have some type of chronic disease need to take medicines every day. And they need to take them appropriately.
"And what we know is that most people don't actually do that very well."
So how do you make sure your elderly and forgetful mum is taking her medication regularly?
According to Proteus, by having that tablet text or even tweet you when it hits the stomach.
This isn't science fiction - although the company appropriately enough shares its name with the Proteus, the microscopic vessel that boldly went where none of us have gone before - inside the human body - in the cult 1960s movie Fantastic Voyage.
Proteus ingestible sensor Small packages: The Proteus ingestible sensor next to a normal drawing pin, to show scale
The key is a tiny ingestible sensor that can be embedded in a tablet. It works like a potato battery.
"If you stick a bit of copper and a bit of magnesium in a potato and you wire it up you can power a lightbulb. It's a simple bit of chemistry that says two dissimilar metals in an ionic solution create an electrical charge," says Mr Thomson.
"What we have done is to take two absolutely required dietary minerals, one is copper and one is magnesium, and put them on a grain of sand that's less than a millimetre square in a way that means that when we combine it with a drug, when you swallow it you become a potato."
The ionic fluid is stomach acid. Enough voltage is created to power the sensor, which communicates with a small plaster-shaped patch worn by the patient, which also tracks vital signs, movement and sleep.
The patch in turn sends all of this data to an application which lives in the cloud. It can be accessed from a smartphone, tablet or PC, and set to send an alert to family, caregivers or healthcare professionals to say the pills have been swallowed.
This is particularly important where the timing is crucial or where missing a few doses means the drug won't work anymore.
Patch, pills and tablet app The band aid shaped patch worn by the patient, which communicates with the Helius app shown on the tablet
"Effectively when you swallow one of our digital drugs it will say, Hello I'm here, I'm Novartis, I'm Diovan, 1.2mg, I'm from plant number 76, I'm batch number 12 and I'm pill number 2." says Mr Thomson.
The application can also track the drug's effects - whether it's been prescribed at the right dosage, or if it simply isn't working.
The technology is being piloted in the UK at High Street chain Lloyds Pharmacy. Patients receive a labelled dosage tray, with an extra pill that contains the sensor. This will record the time each dose is taken, while the tracking patch builds up a picture of their health and movements.
"If you think about a hypertension patient who doesn't take their medicines, the long term result of that will be things like a stroke or a heart attack which may cost the health system tens or hundreds of thousands of dollars," says Mr Thomson.
"And the cost of the medicines is 30p a month. One of the most important things to understand here is that helping people appropriately use medicines has the potential to save hundreds of millions of pounds."
Picture this Dr Patrick Hymel knows only too well the consequences of this type of mistake.
Dr Patrick Hymel (centre) with Dr Stephen Brosette and some of the MedSnap team Dr Patrick Hymel (centre) with Dr Stephen Brosette and some of the MedSnap team
"My grandfather took a medication that he was taking for metastatic prostate cancer incorrectly for almost six weeks," he says.
"Which was kind of devastating to us, that it was for that long. Now at that time he was completely sharp, he was a very smart man, he had all of his faculties, and my aunt, his daughter, was a critical care nurse, and my siblings are both physicians, all three of us are doctors.
"And so we came away from that experience, and I was thinking 'If my grandfather didn't have the support system to be able to take his medications correctly, in a life threatening situation, what are other families struggling with?'."
He and his business partner Dr Stephen Brossette came up with the idea for a smartphone app to identify drugs correctly. But patient error isn't the only thing they wanted to tackle.

Start Quote

Medications are miracles, they allow us to live longer... But the flip side of that is they can also cause harm”
Dr Patrick Hymel MedSnap
Before prescribing drugs, a full medical history is needed, including a run down of the pills and potions someone is already taking.
This can be difficult - people forget to mention things, especially when they're sick or elderly.
Getting this wrong could mean missing a potentially serious interaction between drugs, or a pre-existing medical condition.
Healthcare professionals too can make mistakes.
"About 7% of electronic prescriptions generated in the United States have an error in them. If the doctor writes them down, they have about a 37% error rate," says Dr Hymel.
"Dispensing errors occur about 2-3% of the time. And if I did have the wrong pills, who would ever know? Because the bottle would be labelled with the correct medication name."
MedSnap app in action Say cheese: Drug identification is complicated by the fact that small differences can be detected between batches
The problem is so big it's been estimated it costs the US healthcare system over $200bn each year - or 8% of the country's total annual healthcare expenditure.
The MedSnap ID app uses computer vision to correctly identify nearly 3,500 different drugs. In other words, a doctor or pharmacist takes a photo of all the different tablets a patient is taking, and the app then identifies them. It also flags up any potentially harmful interactions.
"Patients see so many specialists, often the lung doctor isn't talking to the heart doctor and the heart doctor isn't talking to the GI doctor, and medications get confused, interactions can occur. And if no one ever gives a good medication history, they never find out," explains Dr Hymel.
This is complicated technology.
MedSnap screenshot The app is designed for use by healthcare professionals
"Just like the Google autonomous car can tell that the red octagon is a stop sign, we have to be able to tell that the objects that are placed there are pills," he says.
This is harder than it sounds. The app then matches the drugs against a massive repository of identifying data.
"We measure pills to within a tenth of a millimetre. We can interpret over 240,000 shades of colour, and then we read the imprints with some very sophisticated custom-built character recognition technology."
Each pill requires a minimum of 60 images (capsules over 100) drawn from the collections of academic medical centres, hospitals and pharmacy distributors.
The app also learns as more images are taken in the field. The pictures are sent back to the Snap Lab - a team of pharmacy students and pharmacists - to be analysed.
Accuracy is vital, and the company claims the recognition rate is well over 99%.
A version of the app aimed at patients, MedSnap PT is due to be launched in early 2014, and there are plans to use the technology to detect supply chain errors and counterfeit medications.
"Medications are miracles, they allow us to live longer," says Dr Hymel.
"They allow people with many chronic health problems to live independently. But the flip side of that is they can also cause harm."              http://www.bbc.co.uk/news/business-23620996

Are These The Last Days Of The U.S. Marine Corps?

Are These The Last Days Of The U.S. Marine Corps?

Paddy Chayefsky and the Wonders of the Invisible World Part V

 
Welcome to the fifth installment in my examination of the final two films of famed screenwriter Paddy Chayefsky, Network and Altered States. In the first two installments of this series (which can be found here and here) I primarily focused on the former film, with a special emphasis on its rampant, if little addressed, high weirdness. In the third installment I began to start in on Altered States, first examining the feud between Chayefsky and the film's director, cult favorite Ken Russell, as well as offering a synchronicitic interpretation of the names of the major characters.


Chayefsky (top) and Russell (bottom)

In the most recent installment I considered one of the chief inspirations for Altered States, legendary physician, neuroscientist, and psychonaut John C. Lilly, as well as his involvement with a loose association of scientists, psychologists, psychiatrists, and artists centered around one of the most mysterious figures of the 20th century, Andrija Puharich. Puharich was a neurologist and parapsychologist who became a U.S. Army officer in the 1950s and introduced numerous esoteric concepts to scientists of the Edgewood Arsenal. It has been long believed that he developed a relationship with the US intelligence community during this time period as well.


Lilly (top) and Puharich (bottom)

During the 1970s he brought together a rogue's gallery of freethinkers that included figures such as Lilly, Timothy Leary, trailblazing physicist Jack Sarfatti, the famed stage magician Uri Geller, computer scientist and ufologist Jacques Vallee, authors Philip K. Dick and Robert Anton Wilson, among others. While little acknowledged this group would have a profound effect on popular culture, especially within the field of science fiction where big budget productions such as Steven Spielberg's Close Encounters of the Third Kind (Vallee was a technical advisor on the film while the character Claude Lacombe is based upon him) and various Star Trek spinoffs (both the television and film franchises heavily incorporated mythos surrounding The Nine, who were a long time obsession of Puharich's) would incorporate the theories of various individuals affiliated with this network.



As noted in the last installment, which left off with me breaking down the opening moments of the film with a special emphasis on the first meeting between Jessup (William Hurt) and Emily (Blair Brown), there are strong indications that the Puharich circle also influenced Chayefsky's final two films. This is especially true of Altered States whereas Network was more timid in its approach, masking the supernatural elements of its plot line in ambiguity. Indeed, the sequence where I will be picking up --Jessup's venture into rural Mexico in search of the "First Self" via a potent mixture of entheogens --seems partly inspired by similar explorations made by Puharich and other early entheogen researchers.

Jessup and Emily, who soon become married

I'll be working with the assumption that those of you reading this article are already familiar with the plot line of Altered States. For those of you who are not, I strongly advise that you read the rather mediocre plot synopsis on Wikipedia so as not to be totally lost. Anyway, on to the mystical journey into rural Mexico.

To this very day people the world over flock to rural Mexico in search of psychedelic experiences under the watchful eye of a shaman. Sharing peyote with the Huichols (the possible inspiration for Altered States' Hinchi tribe) is apparently a tourist industry unto itself. But the first high profile pilgrimage in search of psychedelics was performed by a New York banker known as R. Gordon Wasson in the mid-1950s.
"On June 29, 1955, a banker by the name of R. Gordon Wasson had stunned the world with his report on the psychedelic experience to be had by ingesting a certain mushroom, a report that appeared in Life magazine later that year. While Mexico taking the mushroom for the first time -- under the traditional setting and with a native shaman --Wasson was supposed to have been participating in a long-distance ESP experiment with Puharich, but as it turned out Wasson was too stoned to be of any use that day. The story generated an enormous amount of interest, coming on the heels of the Huxley's books, The Doors of Perception and Heaven and Hell, which were principally about mescaline. Wasson's experience was with psilocybin, the famous magic mushroom which has been the topic of both learned anthropological studies as well as pop culture accolades. The Life magazine story prompted a young Timothy Leary to go to Mexico in search of the elusive substance itself, and the CIA began an official search for more of it. It was the era of 'God's Flesh.'"
(Sinister Forces Book I, Peter Levenda, pg. 251)
Wasson

Levenda goofed up on the date of the Life article in the above quote --it did not materialized until 1957. According to Lynn Picknett and Clive Prince (who are not always the most reliable sources) Puharich did indeed contact Wasson but whether he sent him on his quest I have been unable to determine. Puharich and Wasson did, however, attempt to conduct some type of experiment involving ESP and magic mushrooms.
"Puharich had settled on the psychoactive drugs used by shamans as the main focus of his research, and in 1953 had contacted R. Gordon Wasson, the first researcher to study the shamanic mushroom cult of Mexico. The two set up an experiment to see if the Mexican shamans, or curanderos, could, under the influence of the mushroom, visit the Round Table Foundation's laboratory in Maine. The long-distance experiment never happened, but it is interesting that Puharich was already thinking in terms of remote viewing..."
(The Stargate Conspiracy, Lynn Picknett & Clive Prince, pgs. 186-187)
Stranger still is the fact that Puharich was wondering around rural Mexico himself in 1956 with famed Dutch psychic Peter Hurkos and possibly Arthur Young, the inventor of Bell Helicopter's first helicopter and a major (if little acknowledged) figure in the early New Age movement. Officially the trip was to locate "certain artifacts" (ibid, pg. 168) at the ancient site of Acambaro.
"In the summer of 1956, Puharich went to Mexico with Peter Hurkos, the famous psychic detective. In Uri, Puharich mentions Hurkos but does not mention Arthur Young on the trip; however other sources say that Young was present, which is entirely likely, but it then raises alarm bells that Puharich left Young's name out of his account... It is possible that Young himself wanted to keep this mission secret, since it took place at a time when the CIA was actively scrounging around the Mexican hinterlands looking for hallucinogenic drugs.
"The archaeological reason given as the cover for their trip was probably bogus, since Acambaro was already known as the site where thousands of pre-Colombian statues had been discovered in the 1930s and 1940s, so there would have been little reason to enlist a psychic detective like Hurkos to search for more of them in the same spot; but... it is entirely possible --no, probable --that Puharich was in Mexico for the same reason: to locate and identify hallucinogens for the Agency. Hurkos what have been along for cover, painting the trip as purely some whacked-out psychic archaeological dig..."
 (Sinister Forces Book I, Peter Levenda, pgs. 250-251)

Hurkos (top) and Young (bottom)

Thus, Puharich was potentially wondering around rural Mexico in search of psychedelics (possibly on the behest of the US intelligence community)  a full year after Wasson made his faithful journey. As far as Altered States is concerned, it would seem that the Wasson expedition is a far more likely inspiration than Puharich's mysterious excursion into Acambaro.

Wasson made his trek with one companion, a Allan Richardson, and experienced a traditional mushroom rite conducted by a female shaman whom they had originally met in the mountains. Jessup makes his trip with a Dr. Echeverria (Thaao Penghlis), who leads him to the Hinchi tribe. They reside atop a mountain featuring rock formations that look suspiciously like mushrooms. During the hike into the mountains Echeverria describes the components of a potent psychedelic brew the Hinchi drink for their vision quests. They include: amanita muscaria (arguably the most well known type of magic mushroom), belladonna (which Echeverria believes yields the alkaloid atropine and/or scopolamine in the Hinchi brew) and the sinicuichi plant.

the shaman and the mushroom-like rock formations

All three substances have been associated with ritualistic uses for centuries. By the time Chayefsky was working on the novel version of Altered States famed poet, novelist and mythologist Robert Graves had already linked amanita muscaria use to the cults surrounding Dionysus in ancient Greece and even suggested that the legendary Eleusinian Mysteries employed amanita muscaria or some other type of psychedelic mushroom in it's sacred rituals.
"... a secret Dionysiac mushroom cult was borrowed from the native Pelasgians by the Achaeans of Argos. Dionysus's Centaurs, Satyrs and Maenads, it seems, ritually ate a spotted toadstool called 'flycap' (amanita muscaria), which gave them enormous muscular strength, erotic power, delirious visions, and the gift of prophecy. Partakers in the Eleusinian, Orphic and other mysteries may also have known the panaeolus papilionaceus, a small dung-mushroom still used by Portuguese witches, and similar in effect to mescaline."
(The White Goddess, Robert Graves, pg. 45)
amanita muscaria, also known as fly agaric

Belladonna, specifically alkaloids that can be produced from it such as atropine and scopolamine, has been known to cause hallucinations for centuries. It is widely believed that belladonna and other like plants were used by the Medieval witch cults of Europe in their rituals.
"Scopolamine, a chemical variant of atropine, is a multi-purpose alkaloid derived from solanaceae plants such as henbane, deadly nightshade, datura, belladonna, and mandrake. The drug had long been one that found its way into myths and folklore: in Norse legends it was used to summon powerful gods; Shakespeare's witches stirred steaming pots of nightshade; Machiavelli penned a comedy about Mandrake; American comic book characters donned noms de plume derived from the plants; and Carlos Castaneda's Don Juan made ample use of the drug."
(A Terrible Mistake, H.P. Albarelli Jr., pg. 214)
belladonna plants

The sinicuichi plant, sometimes known as the Elixir of the Sun, has been used by native tribes all throughout the Americas for centuries though it has generally been neglected by the drug culture of the United States. While it has been known to cause mild hallucinations apparently the most striking characteristic of the sinicuichi plant is its perceived ability to help the user recall past events, even events that happened before the user's birth. This concept plays heavily into Altered States' plot line, its final acts revolving around Jessup's quest to psychologically (as well as physically) regress to the Dawn of Man.

the sinicuichi plant

After Echeverria gets the "okay" from the shaman he and Jessup follow the holy man into a cave at dusk for the ritual. Naturally the opening of the cave resembles the cap of a mushroom, as does a rock formation within the enclosure. This rock formation features cave drawings of what are either skulls or the faces of ghosts. These images are also scrawled upon the walls of the cave throughout and look eerily like the head of a grey aliens. This is most striking, as in 1980 (when Altered States was released)  the meme of the fearsome grey extraterrestrials had just begun to grip the popular consciousness --extraterrestrials in the post-World War II era had generally been depicted in humanoid form (frequently as Aryan supermen) prior to the 1980s.

When the ritual starts Jessup and Echeverria gather around a pot hanging over a campfire where the shaman and several other members of the tribe have congregated. The Hinchi brew is seemingly finished when Jessup is asked to hold a root in his hand. As he is doing so the shaman picks up a ritual knife and slashes an area on his hand between his ring and middle fingers. The shaman then holds the slashed hand (which is also holding the root) over the pot and allows Jessup's blood and the root to fall into the mixture. Some shamans of the Americas (such as those found in certain regions of Peru) use blood as an offering to the spirits they invoked during their rituals. This wound will later play a significant role in Jessup's hallucination.


After its infliction Jessup recoils, retreating with Echeverria to a corner of the cave where his guide bandages the wound. When Jessup looks at the tribe again he finds that they have moved away from the pot and have gathered around an even larger fire with other members of the tribe deeper in the cave. After exchanging a glance with the shaman, Jessup returns to the pot and drinks the strange brew.


The drugs take effect immediately as he is standing up. Primitive special-effects that appear to be fireworks explode throughout the cave, undoubtedly meant to invoke the sensation of jumping to "lightspeed" magic mushrooms generate at the onset of a trip. As soon as this sensation sets in Jessup notices another cave drawing, only this one depicts a naked man and woman standing before a giant mushroom. A lizard  hangs from the stem of the mushroom and is offering a smaller mushroom to the couple. This image will become highly important to Jessup's hallucination.


From their Jessup begins to see visions of the Hinchi, some of them wearing masks, doing a ritualistic dance before the rock formation that resembles a mushroom. They appear to be worshiping it. As Jessup is watching this unfold he begins to catch glimpses of himself and Emily sitting at a table featuring a sun umbrella in a pristine field filled with flowers. They are both dressed in elegant clothing, all of which is entirely white. This gives them the impression of an aristocratic couple sporting their Sunday best.

In between this image of himself and Emily and the visions of the Hinchi doing their ritual dance, Jessup begins to see a serpent extending its head forward. When Jessup returns to the scene of himself and Emily in the field a cup of what appears to be sherbet is sitting before her. She takes a spoonful of it and happily begins to eat. A moment later she extends a spoonful of sherbet to Jessup and he too reluctantly begins to eat.

Sparks begin to fly from the mushroom shaped rock formation, the Hinchi still dancing frantically before it. Undoubtedly this is meant to represent the illumination Jessup and Emily are undergoing. Back in the field Jessup sees visions of Emily kissing him passionately intercut with images of the snake wrapping its coils around him. The dancing and Emily's kisses become more frantic as the snake crushes the life out of Jessup. Then an explosion seemingly occurs around the mushroom/rock formation as beams of illumination fly everywhere. A vision of a man and woman worshipping a giant mushroom against the back drop of the cosmos appears before Jessup.


Clearly the above described sequence is meant to represent the Fall of Man in the Garden of Eden, only here a mushroom (in the form of a cup of sherbet) takes the place of the forbidden fruit. In recent years this is a notion that has become increasingly popular amongst researchers of entheogens.
"As soon as the woman was made we find her in front of the forbidden tree, the tree of knowledge, where she encounters a serpent. It has been mentioned that Soma was likened to a serpent sloughing its skin, and we have seen that the fly agaric sometimes 'sloughs' its outer skin when it pushes up out of the ground; sometimes, when the mushroom doesn't completely broach the enclosing leaves or pine needles that cover it, and opens its cap beneath them, the cap can resemble the flattened head of a pit viper... The stock of the mushroom is also snakelike in its shape, and especially so when it rises out of a hole in pine needles or other leaves. If such a specimen is carefully harvested it leaves a perfectly round opening that looks like a snake hole. Snakes are said to live among the roots of trees, just as the fly agaric does. The fly agaric is the serpent at the foot of the tree of knowledge.
"If the fly agaric is the serpent, then what is the fruit? Where did Eve first spy the fruit when she stood beneath the tree? Up in the branches, out of reach? Or on the ground, where one always finds the ripest fruit, down among the serpents. As much as the fly agaric might look like a serpent on occasion, it more often appears to be a ripe, round  fruit that has fallen from the tree above it. It is an actual fruit, the fruiting body of the mushroom mycelium, and it resembles fruits that humans eat.
"When Eve approached the tree she first saw a serpent, and then the serpent started talking about the eating of fruit. In other words, the presence of the 'snake,' upon examination, suggest the eating of fruit. When one finds the right tree, there will be serpents that offer fruits and fruits that look like serpents, and both will be the fly agaric mushrooms. The presence of the snake in the story also informs us that there is a certain danger involved if the serpent-fruit is eaten: it is possible to feel as poison from eating it as from being bitten by a viper, especially if it is eaten in its fresh state.
"The reputation of the fruit was that it was deadly poison, but the man and woman ate it anyway, and it opened their eyes. Having one's eyes opened is positive, not negative, and in common speech implies gaining helpful and formerly hidden knowledge. In spiritual parlance it means enlightenment, passing from darkness into light. The knowledge of good and evil and the ability to discriminate between them is the gift as well as the burden of such enlightenment, signaling the end of innocence and the beginning of real maturity. It is the knowledge one needs to survive and prosper in a dangerous world. Eating the fruit of enlightenment is the active lifted Adam and Eve above the level of the other animals. It made them godlike, as the story says. Now capable of subtle reflection, they realized their lives would one day come to an end. The idea of death had not even occurred to them before this, but now they saw things clearly. And in the clarity of this new knowledge they may have sensed that life in some form never ends."
(Magic Mushrooms in Religion and Alchemy, Clark Heinrich, pgs. 68-69)

When the vision of the man and woman bowing before the cosmic mushroom fades Jessup finds himself and Emily back in the field. They are now dressed in red as they rise from the table and walk into the field, which has now become a desert. Jessup briefly breaks from this image and pulls at the bandage around his hand, exposing the wound. He sees particles of light coming out of the wound and then returns to the vision of the field. Now he and Emily, still dressed in red, are standing before a mushroom cloud presumably brought about by a nuclear bomb.


The implications of this sequence are seemingly in line with Terence McKenna's theory of the "Stoned Ape" evolutionary model. In his 1992 book Food of the Gods McKenna proposed that human evolution, especially the nearly tripling of human brain size over the last three million years, was a direct result of the human species discovering entheogens.
"My contention is that mutation-causing, psychoactive chemical compounds in the early human diet directly influenced the rapid reorganization of the brain's information-processing capabilities. Alkaloids in plants, specifically the hallucinogenic compounds such as psilocybin, dimethyltryptamine (DMT), and harmaline, could be the chemical factors in the protohuman diet that catalyzed the emergence of human self-reflection. The action of hallucinogens present in many common plants enhanced our information-processing activity, our environmental sensitivity, and thus contributed to the sudden expansion of the human brain size. At a later stage in this process, hallucinogens acted as catalysts in the development of imagination, fueling the creation of internal stratagems and hopes that may well have synergized the emergence of language and religion."
(Food of the Gods, Terence McKenna, pg. 24)
McKenna apparently first got an inkling of this notion due to experiments Roland Fischer conducted in the late 1960s that seemed to reveal that graduate students performed better at detecting the moment when previously parallel lines become skewed after small doses of psilocybin. McKenna began to wonder if this indicated that hallucinogens improved mental capabilities.

McKenna and his work did not began to receive wide exposure until the 1980s, but Robert Anton Wilson mentions him and his brother Donald in the first volume of his Cosmic Trigger (which was released in 1977) series. Whether or not the McKenna brothers were a part of the Puharich network is difficult to say but their research would certainly have been of interest to such individuals. The descriptions Wilson gives of the work the McKenna brothers were doing in the 1970s would seem to indicate that Chayefsky was aware of their research and may even have incorporated some of it into Altered States.
"Briefly, the McKennas regard our universe is a hologram, created by the interaction of two hyper-universes, just as an ordinary hologram is created by the interaction of two lasers. One consequence of this model is that, if our universe is a hologram, every part contains the information of the whole, as in normal holography...
"But the McKenna theory goes far beyond this. There are 64 time-scales in the hologram of our universe, they say, and each one is related to one of the 64 (8 x 8) hexagrams of the I Ching. What we call 'mind' or 'consciousness' is a standing wave form in these 64 time-systems. As the two hyper-universes making up the hologram of our known universe interact in time, 'mind' manifests further in our continuum. This means, in concrete physical terms, that the quantum bonds of the DNA are evolving faster and faster. We are ridinging not one but 64 evolutionary waves all mounting towards a cosmic Awakening...
"The action of psychedelics, in the model, opens the quantum information systems within the DNA to inspection by the higher neural centers. When Dr. John Lilly says he has traveled in time with LSD, and then adds that this is 'only' a metaphor, he is perhaps too modest. If the McKennas are right in their basic theory, every psychedelic trip is literally a voyage through the quantum information system at faster-than-light velocity, i.e., outside time in the local (Einsteinian) universe."
(Cosmic Trigger Volume I, Robert Anton Wilson, pgs. 216-217)
Terence McKenna

The notion of traveling through time via psychedelics, both psychologically and physically, is of course a crucial part of Altered States' third act. Thus, we find allusions to the McKenna "Stoned Ape" theory over a decade before such notions gained widespread exposure in popular works. This further reinforces my belief that Chayefsky was incorporating concepts the Puharich network were discussing into Altered States, though whether this was through direct interaction with the network or from picking up such concepts secondhand, I know not.

But back to the film. When Jessup looks back to his hand, a lizard now resides over the wound where previously beams of light had been flowing from. The lizard disappears from his hand just as suddenly as it appeared but when Jessup looks around again he finds an even larger lizard sitting before him. A moment later this lizard transforms into a naked Emily, who adopts an almost reptilian pose before her husband. The wind begins to kick up and both Emily and Jessup are covered in sand.  As the winds continue to blow eventually their forms themselves begin to dissolve, becoming simply more dust lost in the winds.


The lizard shares much of the same symbolism with the serpent and is frequently interchangeable. In this sequence I interpret the lizard to represent the Kundalini, which Kenneth Grant described as "the Magical Power in the human organism" (The Magical Revival, pg. 220). In some occult traditions, especially those associated with Crowley, this divine serpentine energy combined with physical matter to create the crafty ape known as man. Crowleyian tradition holds that "strange drugs" are highly effective at awakening this force.
"It is the serpent called Kundali, or Kundalini, in the Indian mystery; it is said to be coiled at the base of the spine, and remains dormant in the spiritually unawakened person. In The Book of Law it is unequivocally identified with Hadit, or Set. Practices designed to awaken this power are known to be dangerous; the foolhardy alone undertaken without due magical preparation. Kundalini, awakened, vitalizes the marmas and imbues them with nectar (or, maybe, the venom) of its serpent-kiss. The mingling of the nectar with the fluid surrounding the sacred lotus at each marma generates a kala of great potency. The nature and position of the lotus will determine the type of vision experienced. If the sakti plays in the psycho-sexual centres exclusively, depravity and destruction inevitably result, but if the serpent is raised erect and surpasses all the lotuses during its upward flash, and if it then unites with the nectar dripping from the thousand petalled lotus in the cerebral region, illumination ensues and the highest initiations result. The technique of the process is contained in The Book of Law, and the strange drugs mentioned ... probably referred to the inhibition of the kalas themselves."
(The Magical Revival, Kenneth Grant, pgs. 125-126)

Thus, when Jessup is confronted with the lizard he is facing the divine/spiritual nature of humanity. When the lizard turns into Emily he is then confronted with the material aspect. This is further reinforced by their duel disintegration via the sands of time ("ashes to ashes, dust to dust"). This is of course an idea that is at the heart of Gnosticism and a notion that the film further explores in its third act. For the time being I shall refrain from addressing the Gnostic obsession with spirit and matter but keep in mind that it is crucial to understanding the plot line of this film.


The next morning Jessup awakens to find himself in the desert with a dead lizard that he killed during his hallucinations. Killing a symbolic personification of the divine is surely an ill omen, but he does not heed it. Instead, Jessup acquires a sample of the Hinchi brew and returns to Harvard where he and Arthur (Bob Balaban) can experiment with it under more "clinical" conditions. This is a nice touch by Chayefsky as Boston's Harvard University was at the forefront of research into psychedelic plants for decades.
"Throughout the next thirty-five years the Harvard group meticulously investigated and published all instances of psychoactive plant usage that came to their attention. This body of now continuously expanding work --an integrated body of taxonomic, ethnographic, pharmacological, and medical information -- constitutes the core of the data base currently in global use.
"The birth of ethnopsychopharmacology took place at Harvard... much of it during the turbulent years when Timothy Leary was also at Harvard and attracting a very different sort of reputation through his own effort to place the psychedelic experience on the social agenda."
(Food of the Gods, Terence McKenna, pgs. 241-242)

Leary is of course, as noted above, another figure long associated with the Puharich group, making Harvard a most appropriate location for Altered States' final acts. Things get underway with Jessup taking more of the Hinchi brew in a laboratory under the close supervision of Arthur. Initially his trips are horrific, littered with imagery taken from Dante's Inferno and the Book of Revelation. The audience is shown scenes of this almost immediately after Jessup returns from Mexico. Images of eternal torment in hell, thousands of crucifixions (several schools of Gnostic thought have interrupted the crucifixion as spirit crucified in matter), and so forth fill the screen. I take this sequence as a warning to Jessup about what awaits if he continues to breach the boundaries of human consciousness. One of the most striking images of Jessup's Purgatory trip is the appearance of a Black Sun, a concept with ample symbolic meaning.
"The Black Sun is the sun in its nightly transit, when it leaves this world to shed its light upon another. The Aztecs depicted the Black Sun carried on the back of the god of the Underworld. It is the antithesis of the midday Sun, as maleficent and destroying absolute death...
"Alchemists saw the Black Sun as unworked, primal matter, still to be set on the path of development. To the psychoanalyst, the Black Sun stands for the unconscious, again in its most elemental form.
"Traditionally be Black Sun presages the unleashing of destructive forces upon the universe, society or the individual. It heralds disaster, suffering and death, the inverted image of the noonday Sun, hence the universal sense of ill omen attaching to eclipses."
(Dictionary of Symbols, Jean Chevalier & Alain Gheerbrant, pgs. 951-952)

Both the alchemical and traditional interpretations of the Black Sun are most apt for Jessup at this point in the film. He has just begun his initiation, and thus his consciousness is just beginning to break out of a state of primal matter in search of the divine. And indeed, he is about to unleash incredibly destructive forces upon all those around him. This makes the final image the audience sees from this hallucination most appropriate: a lizard while Jessup babbles "Abaddon" in the background. Abaddon is of course a place/figure with much Biblical significance. The Catholic Encyclopedia notes:
"Hebrew word signifying:
  • ruin, destruction (Job 31:12);
  • place of destruction; the Abyss, realm of the dead (Job 26:6; Proverbs 15:11);
  • it occurs personified (Apocalypse 9:11) as Abaddon and is rendered in Greek by Apollyon, denoting the angel-prince of hell, the minister of death and author of havoc on earth. The Vulgate renders the Greek Apollyon by the Latin Exterminans (that is, "Destroyer"). The identity of Abaddon with Asmodeus, the demon of impurity, has been asserted, but not proved.
In Job 26:6, and Proverbs 15:11, the word occurs in conjunction with Sheol."

In this context I take Abaddon to be a location/state of mind the Kundalini force is about to take Jessup to test his mettle. In the next installment of this series we shall finally break down the striking sequence of events that unfold at Harvard University that will reveal the secrets of mind and matter to Jessup and nearly lead to his destruction. Stay tuned.

OLD SYSTEM(DEBT) VS NEW SYSTEM (EQUITY): CATHERINE AUSTIN FITTS

OLD SYSTEM(DEBT) VS NEW SYSTEM (EQUITY): CATHERINE AUSTIN FITTS

Dotcom: Surveillance and Copyright Extremism Will Cost United States Dearly


In response to growing fears of government spying, yesterday Kim Dotcom announced that parts of his company will relocate to Iceland if that means keeping customers’ data secure. Speaking with TorrentFreak, Dotcom says that continued broad surveillance will have serious financial consequences. “Mass surveillance and copyright extremism will cost the US economy more than any terrorist attack or piracy,” he predicts.
dotcom-prezAs the Edward Snowden fallout continues, yesterday Kim Dotcom revealed that if certain new surveillance laws are passed in New Zealand he will have little choice but to relocate some of Mega’s operations overseas.
Privacy and security have become a hot topics for Dotcom. He was a surveillance target not only for the United States but also for local security service GCSB. Dotcom is tied up in a legal battle with the latter after a court found they monitored him illegally.
With Mega billed as ‘The Privacy Company’, Dotcom has a vested interest in battling the level of spying that can be carried out by the New Zealand government. Speaking with TorrentFreak, Dotcom explains why he sees the powers granted by these proposed new laws as a threat.
“The US government and the other Five Eyes partners (UK, Canada, Australia and New Zealand) have an agreement to push for new spy legislation that will provide them with backdoors into all Internet infrastructure and services. The NZ government is currently aggressively looking to extend its powers with the GCSB and the TICS act, which will force service providers with encryption capabilities to give them secret decryption access,” Dotcom explains.
Immediately it’s clear why this is an issue for Dotcom. All files uploaded to Mega are encrypted to the point where not even the company knows the data it’s carrying. Should the new legislation be introduced all that would have to change, but Dotcom says that isn’t going to happen.
“Mega doesn’t have decryption keys by design and we never will. Privacy companies like Mega will have to look for jurisdictions that care about basic human rights like privacy and freedom of speech,” he says.
Dotcom doesn’t go into detail on a full list of good candidates but says that smaller nations, particularly those with few enemies that don’t need a large spy apparatus, could be a good choice. However, one in particular stands out.
“Iceland is a friendly small country without enemies. They don’t spy on the world and they don’t care. It’s countries like Iceland that will see a rise in Internet services. There is a huge opportunity for smaller nations because the business that is going to leave the US is looking for a new home,” he predicts.
But while the small flourish, Dotcom says that the approaches taken by the ‘Five Eyes’ countries will see them ruin the growth of their own IT industries. And it seems that the United States will suffer the most.
“I expect that more and more Internet businesses will find the hostile US environment unbearable and will move their business elsewhere. Who wants to store any sensitive data on US based servers anymore?
“Over the next 10 years you will see a decline of US Internet giants and the rise of non-US Internet companies that care about user privacy. We will not see a strong NSA like before the Snowden leaks again. The truth is out there and when politicians and laws can’t protect our basic human rights, innovation and friendly jurisdictions will save us,” he says.
But can a country like Iceland cope with such a large influx of technology companies given their current infrastructure?
“Iceland has limited connectivity,” Dotcom admits. “But for now it’s a great option. Others will arise. I am sure of that. We have already setup a company in Iceland.”
So with preparations already underway should the worst-case scenario present itself, does it follow that Mega will desert the land of the Kiwis entirely? Dotcom told TorrentFreak that eventuality is unlikely but if any of their services face government demands for backdoors they will relocate elsewhere. Rest assured though, that won’t be in the United States.
“The US is on a path of destroying its massive lead in the Internet economy. Mass surveillance and copyright extremism will cost the US economy more than any terrorist attack or piracy,” Dotcom says.
“Remember, move your Internet business to small nations that are free of conflict and therefore don’t have a massive spy agenda. Look for countries that have robust privacy and human rights laws. Stay out of the US. Don’t even host a single server there,” Dotcom concludes.

Revealed: Obama admin’s nonsensical legal justification for bulk collection of Americans’ phone records | The Daily Sheeple

Revealed: Obama admin’s nonsensical legal justification for bulk collection of Americans’ phone records | The Daily Sheeple

Monsanto can sue farmers when GMO contamination goes over one percent of their crop | The Daily Sheeple

Monsanto can sue farmers when GMO contamination goes over one percent of their crop | The Daily Sheeple